神经垂体颗粒细胞瘤1例报道并文献复习

目的探讨伴有临床症状的鞍区颗粒细胞瘤(GCT)的病理组织学起源及治疗方法。方法回顾性分析常熟市第二人民医院2022年1月收治的1例鞍区GCT患者的治疗状况和病理结果，并结合关于鞍区GCT病理和治疗的相关文献报道，探讨鞍区GCT肿瘤病理组织起源和治疗要点。结果该患者术前影像学报告怀疑鞍区垂体腺瘤卒中，增强核磁共振成像（MRI）可见占位明显强化，并采取神经内镜辅助下经鼻蝶入路手术切除，术后病理证实为神经垂体颗粒细胞瘤，术后患者症状缓解。结论鞍区GCT很可能起源于神经垂体组织，伴有临床症状的鞍区GCT治疗首选手术，术后定期随访鞍区影像及垂体激素水平。

Objective To investigate the histopathological origin and treatment of granular cell tumor(GCT) in sellar region with clinical symptoms. Methods The treatment process and pathological results of a patient with sellar GCT admitted to the No.2 People’s Hospital of Changshu in January 2022 were analyzed retrospectively. The origin of pathological tissue and treatment methods of sellar GCT tumor were discussed in combination with related literature reports on pathology and treatment of sellar GCT tumor. Results The imaging report of the patient suspected apoplexy of pituitary adenoma in sellar region, and enhanced MRI showed an obvious enhancement of the tumor. The endoscopic endonasal transsphenoidal tumor resection surgery was approached and the postoperative pathology confirmed a neurohypophysis granular cell tumor. The patient was relieved post to the surgery. Conclusion Sellar region GCT is likely to originate from neurohypophysis tissue. Surgery is the priority choice for sellar region GCT with clinical symptoms. The sellar region image and pituitary hormone level are regularly followed up after the surgery.