中国南京持续性植物状态评分量表在急性意识障碍患者的应用

目的探讨中国南京持续性植物状态评分量表（CNPVSS）对急性意识障碍（DOC）患者评估的信度和效度。方法选择2020年1月—12月在南京紫金医院入院接受早期重症康复治疗、病程≤28 d、符合入组条件的253例DOC患者，分别用格拉斯哥昏迷评分量表（GCS）和CNPVSS进行评分，计算不同性别患者GCS和CNPVSS评分结果的相关性，并且对比分析两个量表的信度和效度。结果入组患者的DOC程度较重，气管切开率在80%左右。GCS评分结果男性为8（6，10）、女性为8（5，10），CNPVSS评分结果男性为3（2，7）、女性为3（1，6）；两个量表评分结果在男女均有统计学显著相关（P<0.001）。CNPVSS的信度指标克朗巴赫α系数（男0.905，女0.882）高于GCS（男0.580，女0.665）；效度指标Kaiser-Meyer-Olkin（KMO）值（男0.846，女0.834）也高于GCS（男0.559，女0.593）。结论CNPVSS可用于急性DOC患者评估，且有较好的信度和效度。

Objective To explore the reliability and validity of the Chinese Nanjing persistent vegetative state scale(CNPVSS) in evaluating patients with acute disorders of consciousness(DOC). Methods 253 DOC patients who were admitted to Nanjing Zijin Hospital from January to December 2020 for early severe rehabilitation treatment, with a course of ≤28 days and meeting the admission criteria were selected, and scored by using the Glasgow Coma Scale(GCS) and CNPVSS respectively. The correlation between GCS and CNPVSS scores of patients of different genders was calculated.The reliability and validity of 2 scales were compared and analyzed. Results The extent of DOC in enrolled patients was relatively severe, with a tracheotomy rate of around 80%. The GCS score results were 8(6,10) for male and 8(5,10) for female, while the CNPVSS score results were 3(2,7) for male and 3(1,6) for female. The scores of 2 scales were significantly correlated in both genders(P<0.001). The reliability index of CNPVSS, the Cronbach’s alpha coefficient(0.905 for males and 0.882 for females) were higher than GCS(0.580 for males and 0.665 for females). The Kaiser Meyer Olkin(KMO) value of the validity indicator(0.846 for male, 0.834 for female) was also higher than GCS(0.559 for male, 0.593 for female). Conclusion CNPVSS can be used for the evaluation of acute DOC patients and has good reliability and validity.