手术治疗2例脑膜血管瘤病致难治性癫痫临床病例分析并文献复习

【摘要】目的探讨脑膜血管瘤病(MA)致难治性癫痫的手术疗效。方法回顾性分析2例经病理证实为MA患者的临床资料。病例1患者间歇期脑电图为正常脑电图，但患者存在明确临床发作；病例2患者同时并发灰质异位；二者均在术中皮层脑电监测下行病灶切除。结果手术过程顺利，术后恢复良好，术后随访1年为Engle Ⅰ级，生活质量较前提高。结论手术治疗MA引起的难治性癫痫有确定疗效。

Abstract: Objective To investigate the surgical effect of refractory epilepsy caused by meningioangiomatosis(MA). Methods The clinical data of 2 patients with MA confirmed by pathology were analyzed retrospectively. In case 1, the EEG in intermittent period was normal, but the patient had definite clinical attack. Case 2 was complicated with gray matter heterotopia at the same time. Both lesions were resected under intracranial cortical EEG monitoring. Results The operation process was smooth and the postoperative recovery was good. The postoperative follow-up for 1 year was Engle grade I, and the quality of life was improved. Conclusion The surgical treatment of refractory epilepsy caused by MA has a definite effect.