3D-TOF-MRA与3D-FIESTA联合3D-TOF-MRA对面肌痉挛术前评估价值比较的Meta分析

目的以微血管减压术（MVD）为金标准，利用Meta分析方法评价并间接比较3D-TOF-MRA与3D-FIESTA+3D-TOF-MRA对单侧血管压迫性面肌痉挛的术前评估价值。方法计算机检索维普网、万方、知网、PubMed、Cochrane Library、Web of Science、Embase等数据库中的相关文献，采用Review Manager 5.4、Meta-disc 1.4和Stata 12.0软件进行Meta分析，利用相对比值间接比较二者的评估价值。结果经筛选本研究共纳入文献11篇，共计600例患者。Meta分析结果显示，对于单侧血管压迫性面肌痉挛术前评估价值，3D-FIESTA+3D-TOF-MRA与3D-TOF-MRA的Sen合并、Spe合并、+LR、-LR、DOR分别为0.97（95% CI:0.95~0.99），0.85（95% CI:0.81～0.88），6.15（95% CI:4.26~8.87），0.04（95% CI:0.02~0.08），168.23（95% CI:73.19~386.72）与0.89 (95% CI:0.85～0.93)，0.72（95% CI:0.66～0.78），3.66（95% CI:12.24~5.99），0.13（95% CI:0.06~0.3），29.21（95% CI:10.38~82.17）。3D-FIESTA+3D-TOF-MRA与3D-TOF-MRA间接比较结果RDOR为5.76（95% CI:4.71～7.05）。结论在单侧血管压迫性面肌痉挛术前评估方面，3D-FIESTA+3D-TOF-MRA相较于3D-TOF-MRA具有更高的诊断准确性。

Objective Taking microvacular decompression(MVD) as the gold standard, 3D-TOF-MRA and 3D-FIESTA+3D-TOF-MRA were indirectly compared by Meta analysis on unilateral vascular compression hemifacial spasm. Methods The relevant documents in Weipu, Wanfang, CNKI, PubMed, Cochrane Library, Web of Science and Embasewere systematically retrieved. Review Manager 5.4, Meta -disc 1.4 and Stata 12.0 software were used for Meta analysis. The results of indirect comparison were compared by relative ratio. Results After screening, this study included 11 documents with a total of 600 patients. Meta analysis results showed that for the preoperative evaluation value of unilateral vascular compression hemifacial spasm, the Sen merge, Spe merge, +LR, -LR, DOR of 3D-FIESTA+3D-TOF-MRA and 3D-TOF-MRA were respectively 0.97(95% CI:0.95-0.99), 0.85(95% CI:0.81-0.88), 6.15(95% CI:4.26-8.87), 0.04(95% CI:0.02-0.08), 168.23(95% CI:73.19-386.72) and 0.89(95% CI:0.85-0.93), 0.72(95% CI:0.66-0.78), 3.66(95% CI:12.24-5.99), 0.13(95% CI:0.06-0.3), 29.21(95% CI:10.38-82.17). The RDOR of the indirect comparison between 3D-FIESTA+3D-TOF-MRA and 3D-TOF-MRA was 5.76(95% CI:4.71-7.05). Conclusion Compared with 3D-TOF-MRA, 3D-FIESTA+3D-TOF-MRA has higher diagnostic accuracy in the preoperative evaluation of unilateral vascular compression hemifacial spasm.